Multi-ion versus single-ion conduction mechanisms can yield current rectification in biological ion channels
نویسندگان
چکیده
منابع مشابه
Multi-ion versus single-ion conduction mechanisms can yield current rectification in biological ion channels.
There is clear evidence that the net magnitude of negative charge at the intracellular end of inwardly rectifying potassium channels helps to generate an asymmetry in the magnitude of the current that will pass in each direction. However, a complete understanding of the physical mechanism that links these charges to current rectification has yet to be obtained. Using Brownian dynamics, we compa...
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ژورنال
عنوان ژورنال: Journal of Biological Physics
سال: 2014
ISSN: 0092-0606,1573-0689
DOI: 10.1007/s10867-013-9338-4